Simulations and Image Reconstruction for the High Resolution CaLIPSO PET Scanner for Brain and Preclinical Studies

Jan 19, 2018
8 pages
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Abstract: (arXiv)
The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm3^3, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET scanner with a "cube" geometry. We quantify by simulations the expected image resolution and Noise Equivalent Count Rates and compare them to the performance of the most efficient clinically used PET scanner, the High-Resolution Research Tomograph by Siemens. We bring up the issues of the image reconstruction for a scanner with high spatial resolution. We also present simulated brain images for [18^{18}F]-FDG and [11^{11}C]-PE2I tracer distributions. Results demonstrate the high potential of the CaLIPSO PET scanner for small animal and brain imaging where combination of high spatial resolution and efficiency is essential.
Note:
  • Submitted to IEEE TRPMS journal, 8 pages, 10 figures
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