XEMIS2 Liquid Xenon Compton Camera for Small Animal 3γ Medical Imaging: Scintillation Light Measurement
- Yuwei Zhu(),
- Stéphane Acounis(),
- Nicolas Beaupère(),
- Jean-Luc Beney(),
- Julien Bert()
- CHRU Morvan
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Abstract: (IEEE)
An innovative XEnon Medical Imaging System, named XEMIS2, consisting of a liquid xenon (LXe) Compton camera, is developed to image small animal with 3γ imaging technique. The main objective of XEMIS2 involves the 3D localization of a radiopharmaceutical labeled with a specific radionuclide 44Sc and the lessening of the administered radiotracer activity while preserving the image quality in oncology diagnosis. XEMIS2 is a monolithic single-phase detector with a large axial Field Of View (FOV), handling up to nearly 200 kg of ultra-high-purity liquid xenon. The XEMIS2 facility has been successfully conceived and developed at the SUBATECH laboratory. In XEMIS2, the scintillation signals provide the γ-rays interaction time. Furthermore, it is possible to pre-localize the γ-rays interactions spatially and then achieve the virtual fiducialization of the active volume by matching the scintillation signals with the ionization signals. In order to measure scintillation light, we distribute a set of PhotoMultiplier Tubes (PMTs) around the surface of the active area. Besides, a self-triggered scintillation light detection chain has been specially developed for XEMIS2 to carry out continuous data taking with negligible electronics dead-time. It is currently calibrated in the prototype XEMIS1. The calibration results indicate that the dedicated detection chain has a good performance in scintillation light measurement. XEMIS2 is recently under construction in a small animal medical imaging center CIMA, for further preclinical studies.- Cameras
- Xenon
- Animals
- Biomedical imaging
- Ionization
- Detectors
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- [6]
- [7]
- [8]
- [9]
- [10]
- [11]
- [12]
- [13]
- [14]